Let’s Talk Niacinamide Serum Benefits

Morgan McHose

Before we get into niacinamide serum benefits, let’s distinguish between niacinamide serum and its oral counterpart, B3 supplements. If you’ve ever walked down a vitamin aisle at a grocery store, you’ve probably seen a bottle (or several) marked B3. Vitamin B3 supplements appear everywhere. It’s unlikely you’ll ever need to partake yourself, however. If you live in the United States, a majority of us hit the recommended dosage of B3 through our diet alone.

The topical B3, a face serum called niacinamide, is a little different. Studies have shown that this nifty serum is capable of improving skin appearance and overall skin health. It’s also a great option for people with sensitive skin. The serum is notably gentle and non-irritating.


There are many niacinamide serum benefits, so let’s jump right in! First off, niacinamide serum hydrates the skin. It might even help regulate how much oil sebum your body makes, which could prevent your skin from becoming too oily. By preventing excess oil and blocking out pollutants, niacinamide serum works to stave off the core causes of acne.

Niacinamide serum also reduces aging signs like wrinkles, sun damage and fine lines. Coupled with retinol, this serum has even been shown to improve upon overall skin texture.


Scientists are still actively researching niacinamide serum to understand more about how it works on a cellular level. There are multiple theories, with varying amounts of evidence, which attempt to answer all that the niacinamide serum achieves within the body. One theory says that extra niacinamide in the body translates to extra NAD+. The molecule NAD+ is extremely important, and one of its many jobs involves the upkeep of our skin. NAD+ works to keep our skin elastic and youthful. Of course, surprise surprise, levels of NAD+ start to go down as we age. The idea is that its precursor, niacinamide, can enable the creation of more NAD+.

It’s important to note that the effectiveness of niacinamide serum is not in doubt. It’s not the niacinamide serum benefits that are being questioned, but rather its methods that are still debated. And there’s a lot we still know about niacinamide serum. For example, people have been testing combination approaches with a variety of skincare products. Vitamin C serum and retinol serum in particular work beautifully in tandem with niacinamide serum.

vitamin c serum


It’s always important to conduct your own research before combining your favorite skincare products. Certain combinations can lead to adverse reactions. However, some combinations magnify the power of the two. Niacinamide and Vitamin C can be used safely in the same skincare session (or even better, in the same products). Other combinations, like glycolic acid and retinol or salicylic acid and retinol, are beneficial together but cannot be used in the same sitting.

And if you can’t afford both skincare products, don’t stress! We don’t want false information online to scare you out of a beneficial combination, but a combination approach isn’t a necessity, either. If you would like to branch out in your skincare routine and are unsure about which to try, we’ll cover the benefits of Vitamin C serum alone before discussing a combination plan. I can’t count how many times I’ve read “you NEED this product” or “the ONE product I can’t live without!” Let’s be real—barring medical exceptions, no one NEEDS a specific skincare product. Don’t let misleading headlines or fearmongering take the reins of your skincare journey. You’re steering this ship! I’m mixing my metaphors, but you get the point.

Niacinamide and Vitamin C in One Product

If you’re deciding between trying out Vitamin C serum or niacinamide serum, it’s hard to go wrong! Both products are extremely effective at what they do. It’s just a matter of what you want most out of your skincare product. And, no matter what you choose, patience will be key. Keep in mind that it can take weeks or even months for results to show.

Your best choice should be a combination of niacinamide and vitamin C in one product. The two-in-one product works very well together. A combination of niacinamide serum and Vitamin C serum can prove extremely effective. The duo, when layered on the skin, evens out skin tone, reduces scar appearance, fights acne, and more.

The best two-in-one serum is Plant Mother’s Vitamin C, containing natural niacinamide derived from organic maracuja and rosehips. It’s completely plant-based and full of nutritious antioxidants. Unlike common Vitamin C face creams, Plant Mother’s serum is loaded with nutrient-rich ingredients. All Plant Mother products use natural ingredients, full of antioxidants and vitamins to enrich and brighten your skin. One powerful natural ingredient is the amazing Kakadu plum. The Kakadu plum has more Vitamin C than oranges—55 times more! This is just one of many stellar ingredients at work in this Vitamin C serum to nourish the skin.

encapsulated retinol


Niacinamide and retinol make up another desirable duo. Traditional retinols are notorious for drying out the skin and causing irritation. The hydrating effects of niacinamide can help prevent the downsides of traditional retinols while simultaneously boosting its anti-aging and acne-fighting benefits.

But if you’re on the hunt for a retinol that doesn’t need a niacinamide serum to keep its side effects in check, consider Plant Mother’s vegan retinol serum. This plant-based retinol combats visible signs of aging, improves skin texture, and rejuvenates the skin. And it does it all without drying your skin out or causing incessant irritation. Plant Mother’s retinol won’t cause you sun sensitivity, either. You may have heard that traditional retinols can cause sun sensitivity, meaning that you’re more likely to burn in the sun. This is unfortunately true, but it’s not the case with vegan retinols. You’ll still need to wear a good sunscreen, but Plant Mother’s vegan retinol won’t cause the dreaded sun sensitivity.

Additionally, all of Plant Mother serums are created with your health and the planet’s health in mind. The company uses locally grown ingredients farmed with strictly green practices. And you’ll never spot a toxin, artificial fragrance, or chemical of any kind in Plant Mother’s ingredients lists. The brand prides themselves on being a chemical-free, synthetic-free brand that relies on what Mother Earth provides. And in return, the company does what they can to protect her. All of their skincare is zero waste, all of the packaging is plastic-free and entirely recyclable.


When it comes to skin health, there are several key niacinamide serum benefits. Niacinamide serum is anti-inflammatory, and an antioxidant, as well. In other words, the serum reduces redness and inflammation of the skin. This makes the product a great option for people with dry or sensitive skin. The serum moisturizes the skin as well, keeping it hydrated and preventing dryness.


Niacinamide serum brightens the skin and evens out skin tone. It can also help combat acne. And of course, one of the most popular niacinamide serum benefits is its anti-aging properties. Be it sun damage, hyperpigmentation, fine lines, or wrinkles, niacinamide serum may help to reduce it.

And, if you subscribe to the niacinamide to NAD+ theory, the serum might even be boosting elasticity and neutralizing free radicals. What are free radicals? Free radicals are, put simply, atoms that prove destructive to the skin due to their unstable nature. The theory goes that more niacinamide leads to more NAD+, which means more molecules available to combat free radicals. This should, in theory, reduce visible signs of aging.


If you have a history of allergies or a specific skin condition, you might want to consult your provider before starting any new skincare product, including niacinamide serum. Side effects for niacinamide serum include redness, swelling, and itchiness. If you’d like to err on the side of caution, you can always do a patch test beforehand. Pick a small, dime-sized area on the forearm and apply a small amount of the new niacinamide serum to the site. Observe for about a full day, or 24 hours. If you experience any adverse reaction, stop using the serum.


Who knew there were so many niacinamide serum benefits? And the gentle serum should work for any skin type, even for those with sensitive skin. Even if you’re a seasoned skincare shopper, we hope you learned something new today! And for the skincare newbies, don’t be intimidated. It’s a lot of information, but you don’t have to learn everything in one day. It might be tempting to try a new skincare routine, with lots of new products all at once, but always keep it to one new product at a time. Give your skin time to adjust and keep an eye out for any adverse reactions. A slow introduction period is recommended for most products, so be sure to do your research about proper application and usage!

The skincare journey is a marathon, not a sprint. Don’t be discouraged if you don’t see immediate results—a lot of products take a while to start showing improvement. No matter your stage in this journey, we’re glad you found your way to us. Good luck!


This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. The publisher of this content does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement, skincare product, or lifestyle program.

Morgan McHose
Morgan McHose is a graduate student at the University of Southern California studying Public Relations and Advertising. When she’s not studying, Morgan loves writing and reading the latest YA fantasy novels. Morgan currently volunteers as a multimedia journalist at the USC Media Center and writes as an opinion staff writer for the USC newspaper. She aims to find a creative career in Los Angeles in entertainment PR.